Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098279 | 0.82 | POLB (0.41) | GRM2SLC13A5SQORPOLBCDC7 | |
| SCHEMBL28295740 | 0.80 | PLA2G10 (0.45) | ALDH1A1MAPTNPSR1USP2HPGD | |
| SCHEMBL28790249 | 0.80 | PLA2G10 (0.45) | ALDH1A1MAPTNPSR1USP2HPGD | |
| SCHEMBL16610961 | 0.78 | LTA4H (0.41) | MAPTHPGDSMN1; SMN2 | |
| SCHEMBL16611199 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1HPGDSLC13A5 | |
| SCHEMBL12794792 | 0.76 | SQOR (0.36) | ALDH1A1MAPTNPSR1USP2HPGD | |
| SCHEMBL22397243 | 0.76 | MAPT (0.42) | ALDH1A1MAPTNPSR1USP2HPGD | |
| SCHEMBL14247665 | 0.75 | GLA (0.39) | — | |
| SCHEMBL6376093 | 0.74 | KDM1A (0.50) | SLC13A5CYP3A4CYP2C9 | |
| SCHEMBL5788308 | 0.72 | PLA2G10 (0.44) | ALDH1A1MAPTNPSR1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014515-A1 | 2, 7 -NAPHTHYRIDIN- 1 -ONE DERIVATIVES AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |