Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL14247469 | 0.80 | LIMK2 (0.34) | GLAKDM1AMAOB | |
| SCHEMBL16610961 | 0.78 | LTA4H (0.41) | GLAKDM1AMAOBLTA4H | |
| SCHEMBL29206981 | 0.75 | KMT2A (0.44) | CA1CA2CA9CA12 | |
| SCHEMBL12873970 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL31556358 | 0.74 | PDE3B (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL6376093 | 0.74 | KDM1A (0.50) | KDM1AMAOBLTA4H | |
| SCHEMBL31525266 | 0.72 | CA2 (0.49) | CA1CA2CA9CA12CA14 | |
| SCHEMBL16611199 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL3808200 | 0.71 | CA1 (0.45) | CA1CA2CA9CA12CA14 | |
| SCHEMBL28866660 | 0.71 | NFE2L2 (0.40) | CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |