Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850591 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12046659 | 0.79 | KDM4E (0.50) | ALDH1A1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL20925016 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL12046633 | 0.76 | ACHE (0.44) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14558121 | 0.75 | MAPT (0.46) | ALDH1A1KDM4EMAPTKMT2AGAA | |
| SCHEMBL20924857 | 0.69 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL20924944 | 0.65 | BRD4 (0.38) | ALDH1A1KDM4EHPGDL3MBTL1MAPT | |
| SCHEMBL20924990 | 0.65 | BRD4 (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15101181 | 0.64 | MEN1 (0.41) | ALDH1A1KDM4EHPGDL3MBTL1MAPT | |
| SCHEMBL12812176 | 0.64 | BRD4 (0.37) | ALDH1A1KDM4EHPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012674-A1 | DIHYDROBENZOINDAZOLES | N.V. ORGANON (NL) | 2011-02-03 | — | — | WO | disclosed |