Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207167 | 0.86 | OPRD1 (0.64) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL12159198 | 0.86 | OPRD1 (0.64) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL18408143 | 0.83 | OPRD1 (0.60) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL3423195 | 0.83 | OPRD1 (0.60) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL1206566 | 0.83 | OPRD1 (0.60) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL972352 | 0.81 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL14619144 | 0.81 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL11710419 | 0.81 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL13014950 | 0.81 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL13589886 | 0.81 | SIGMAR1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028445-A1 | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028445-A1 | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use | XDH, HSD11B1, HSD3B1 | OPRM1 21/4885OPRD1 29/4885OPRK1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.