Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289503 | 0.89 | CNR2 (0.34) | GRM4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL1289362 | 0.88 | MAOB (0.38) | GRM4ALDH1A1MAPTKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL1289492 | 0.76 | MAPT (0.42) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL12473442 | 0.73 | ALDH1A1 (0.36) | CXCR1CXCR2PGK1GRM4ALDH1A1 | |
| SCHEMBL4498559 | 0.73 | APP (0.40) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4506936 | 0.72 | GPR55 (0.39) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL1289348 | 0.69 | CXCR1 (0.48) | CXCR1CXCR2PGK1ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL4499450 | 0.69 | CXCR1 (0.48) | CXCR1CXCR2PGK1ALDH1A1NPC1 | |
| SCHEMBL1289456 | 0.66 | LOXL2 (0.40) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4510137 | 0.64 | METAP1 (0.48) | GRM4ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |