SCHEMBL12895149

SCHEMBL12895149

C=C(C)C(=O)OCC(=O)c1cccc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA6 P23280 1/20 0.43
CA9 Q16790 1/20 0.43
RAB9A P51151 5/20 0.43
MAPK1 P28482 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
PARP1 P09874 1/20 0.42
NPC1 O15118 3/20 0.42
RXFP1 Q9HBX9 1/20 0.41
TNF P01375 1/20 0.41
NOD1 Q9Y239 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12895156 0.82 ESR2 (0.43) ESR2RAB9AKDM4EALDH1A1NPC1
SCHEMBL9018645 0.82 NPC1 (0.54) ESR1ESR2RAB9AMAPK1KDM4E
SCHEMBL12895148 0.81 ALDH1A1 (0.57) ESR1ESR2CA12CA1CA2
SCHEMBL17034384 0.78 RAB9A (0.47) ESR1ESR2RAB9AMAPK1ALDH1A1
SCHEMBL17034386 0.77 THRB (0.46) ESR1ESR2CA12CA1CA2
SCHEMBL7285469 0.77 ESR1 (0.53) ESR1ESR2CA12CA1CA2
SCHEMBL12895147 0.77 ESR1 (0.54) ESR1ESR2CA12CA1CA2
SCHEMBL1904651 0.76 ALDH1A1 (0.44) CA12CA1CA6CA9RAB9A
SCHEMBL10793807 0.76 ADRB2 (0.60) ESR1ESR2RAB9AMAPK1NPC1
Potassium SCHEMBL10377714 0.76 ESR1 (0.51) ESR1ESR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110033804-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-10 US disclosed
US-20110033804-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-10 US disclosed