Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16397618 | 1.00 | CYP2D6 (0.43) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL16397280 | 1.00 | CYP2D6 (0.43) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL16397424 | 1.00 | CYP2D6 (0.43) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL3450044 | 0.82 | CYP2D6 (0.48) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL683739 | 0.82 | CYP2D6 (0.48) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL5861606 | 0.82 | CYP2D6 (0.48) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL3450045 | 0.82 | CYP2D6 (0.48) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL12896187 | 0.80 | THRB (0.36) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL11395522 | 0.76 | CYP2D6 (0.46) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 | |
| SCHEMBL11395542 | 0.76 | CYP2D6 (0.46) | CYP2D6CYP1A2ALOX15CYP2C19SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969678-B2 | Method of producing optically active β-aminocarbonyl compound | DEXERIALS CORPORATION (JP) | 2018-05-15 | — | — | US | claimed |
| US-9687833-B2 | Method of producing optically active compound | DEXERIALS CORPORATION (JP) | 2017-06-27 | — | — | US | claimed |
| US-20160250625-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE COMPOUND | DEXERIALS CORPORATION (JP) | 2016-09-01 | — | — | US | claimed |
| US-20160159729-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ß-AMINOCARBONYL COMPOUND | DEXERIALS CORPORATION (JP) | 2016-06-09 | — | — | US | claimed |
| WO-2014196542-A1 | OPTICALLY ACTIVE COMPOUND PRODUCTION METHOD | デクセリアルズ株式会社 (JP) | 2014-12-11 | — | — | WO | claimed |
| CN-116635054-A | Compounds comprising tetrapeptide moieties | 科比欧尔斯公司 | 2023-08-22 | — | — | CN | disclosed |
| US-9969678-B2 | Method of producing optically active β-aminocarbonyl compound | DEXERIALS CORPORATION (JP) | 2018-05-15 | — | — | US | disclosed |
| US-9687833-B2 | Method of producing optically active compound | DEXERIALS CORPORATION (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20160250625-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE COMPOUND | DEXERIALS CORPORATION (JP) | 2016-09-01 | — | — | US | disclosed |
| US-20160159729-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ß-AMINOCARBONYL COMPOUND | DEXERIALS CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| WO-2014196542-A1 | OPTICALLY ACTIVE COMPOUND PRODUCTION METHOD | デクセリアルズ株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | UNIVERSITETET I OSLO (NO) | 2011-02-10 | — | — | US | disclosed |
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | UNIVERSITETET I OSLO (NO) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | HRH3, HRH4, H1-3 | CYP2D6 1481/4885CYP1A2 1318/4885ALOX15 3446/4885 |
| US-20160159729-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ß-AMINOCARBONYL COMPOUND | PAICS, AAAS, ALG8 | CYP2D6 3698/4885CYP1A2 2035/4885ALOX15 373/4885 |
| US-20160250625-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE COMPOUND | ALOX5, ENO1, EPX | CYP2D6 1845/4885CYP1A2 1715/4885ALOX15 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.