Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884857 | 0.82 | PKM (0.36) | CTSKPKM | |
| Hydrochloric Acid SCHEMBL1218339 | 0.81 | PKM (0.39) | CTSKPKM | |
| SCHEMBL2831684 | 0.76 | CTSK (0.34) | CTSKKMT2A | |
| SCHEMBL1219536 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL13689032 | 0.71 | CTSK (0.49) | CTSKKMT2APKMTSHRHSD17B10 | |
| SCHEMBL1218083 | 0.71 | CTSK (0.49) | CTSKKMT2APKMTSHRHSD17B10 | |
| SCHEMBL12898730 | 0.71 | KDM4E (0.35) | — | |
| SCHEMBL2678471 | 0.69 | DPP4 (0.36) | — | |
| SCHEMBL1218080 | 0.69 | CTSK (0.32) | CTSK | |
| SCHEMBL13689212 | 0.69 | BMP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | CTSK 2324/4885KMT2A 3459/4885PKM 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.