Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 10/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998685 | 0.95 | ALDH1A1 (0.59) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13052998 | 0.91 | ALDH1A1 (0.52) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13998715 | 0.88 | HPGD (0.57) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27200963 | 0.87 | HPGD (0.53) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9867688 | 0.86 | SGMS2 (0.55) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL24454863 | 0.85 | RAB9A (0.58) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30787109 | 0.85 | RAB9A (0.54) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2244448 | 0.85 | NPC1 (0.58) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29686704 | 0.85 | RAB9A (0.58) | HPGDNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9868635 | 0.85 | HPGD (0.54) | HPGDNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875368-B2 | benzoxazole or imidazolopyridine compounds and charge transfer compounds, interposed between a pair of electrodes, to form organic electroluminescent devices, having high emission luminance and efficiency | CANON KABUSHIKI KAISHA (JP) | 2011-01-25 | — | — | US | disclosed |
| US-7875368-B2 | benzoxazole or imidazolopyridine compounds and charge transfer compounds, interposed between a pair of electrodes, to form organic electroluminescent devices, having high emission luminance and efficiency | CANON KABUSHIKI KAISHA (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20080315185-A1 | Photodetector | FUJIFILM CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080138656-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20080138656-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138656-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CRY1, ORC3, OXER1 | HPGD 2176/4885NPC1 3514/4885RAB9A 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.