Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200963 | 0.98 | HPGD (0.53) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL13998685 | 0.90 | ALDH1A1 (0.59) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL13998715 | 0.86 | HPGD (0.57) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL12910410 | 0.85 | HPGD (0.56) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL9867688 | 0.84 | SGMS2 (0.55) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL24454863 | 0.83 | RAB9A (0.58) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL29686704 | 0.83 | RAB9A (0.58) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL30787109 | 0.83 | RAB9A (0.54) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL2244448 | 0.83 | NPC1 (0.58) | HPGDKDM4ENPC1RAB9ATP53 | |
| SCHEMBL4148452 | 0.83 | RAB9A (0.54) | HPGDKDM4ENPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |