SCHEMBL1291102

SCHEMBL1291102

CCCCCC(O)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
FFAR1 O14842 2/20 0.61
CA1 P00915 2/20 0.50
CA2 P00918 1/20 0.50
FFAR4 Q5NUL3 1/20 0.45
SPHK1 Q9NYA1 1/20 0.45
NFKB1 P19838 1/20 0.44
EPHX1 P07099 1/20 0.44
MAPT P10636 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20472582 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL4957808 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL5575803 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL15007853 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL3761975 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL15007874 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL4850662 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL34950 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL13849594 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4
SCHEMBL5575801 0.98 GPR84 (0.65) GPR84FFAR1CA1CA2FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043165-A1 LOW-TEMPERATURE CURING COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2025-02-06 US disclosed
US-20240294780-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2024-09-05 US disclosed
US-20240173320-A1 METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES Epizyme, Inc. 2024-05-30 US disclosed
EP-4363511-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG Industries Ohio Inc. (US) 2024-05-08 EP disclosed
EP-3580290-B1 LOW-TEMPERATURE CURING COATING COMPOSITIONS PPG IND OHIO INC (US) 2024-05-01 EP disclosed
US-11952514-B2 Low-temperature curing adhesive compositions PPG INDUSTRIES OHIO, INC. (US) 2024-04-09 US disclosed
WO-2023279087-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2023-01-05 WO disclosed
CN-112375105-B Application of N, N-coordinated divalent nickel complex containing meta-carborane ligand 上海应用技术大学 2022-08-23 CN disclosed
CN-113646172-A Laminated body 宇部兴产株式会社 2021-11-12 CN disclosed
US-20210213014-A1 METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES Epizyme, Inc. 2021-07-15 US disclosed
EP-1581510-A2 1-ARYL-2-HYDROXYETHYL AMIDES AS POTASSIUM CHANNEL OPENERS Bristol-Myers Squibb Company (US) 2005-10-05 EP disclosed
EP-1581510-A2 1-ARYL-2-HYDROXYETHYL AMIDES AS POTASSIUM CHANNEL OPENERS Bristol-Myers Squibb Company (US) 2005-10-05 EP disclosed
US-20050009921-A1 Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same MARYLAND, UNIVERSITY OF 2005-01-13 US disclosed
WO-2004110989-A1 N-HYDROXY-7-(ARYLAMINO)HEPTANAMIDE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS BAYER PHARMACEUTICALS CORPORATION (US) 2004-12-23 WO disclosed
WO-2004047743-A3 1-ARYL-2-HYDROXYETHYL AMIDES AS POTASSIUM CHANNEL OPENERS BRISTOL MYERS SQUIBB CO (US) 2004-07-29 WO disclosed
US-20040122007-A1 1-aryl-2-hydroxyethyl amides as potassium channel openers BRISTOL-MYERS SQUIBB COMPANY 2004-06-24 US disclosed
US-20040122007-A1 1-aryl-2-hydroxyethyl amides as potassium channel openers BRISTOL-MYERS SQUIBB COMPANY 2004-06-24 US disclosed
WO-2004047743-A2 1-ARYL-2-HYDROXYETHYL AMIDES AS POTASSIUM CHANNEL OPENERS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-06-10 WO disclosed
WO-2004047743-A2 1-ARYL-2-HYDROXYETHYL AMIDES AS POTASSIUM CHANNEL OPENERS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-06-10 WO disclosed
CN-87105781-A ANTIMICROBIAL MIXTURES 1988-03-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040122007-A1 1-aryl-2-hydroxyethyl amides as potassium channel openers KCNQ3, KCNQ2, KCNQ4 GPR84 503/4885FFAR1 212/4885CA1 1173/4885
US-20050009921-A1 Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same SLC26A3, SLC22A8, SLC43A1 GPR84 1156/4885FFAR1 1701/4885CA1 1259/4885
US-20240173320-A1 METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES EHMT2, BHMT2, BHMT GPR84 2967/4885FFAR1 4405/4885CA1 4209/4885
US-20210213014-A1 METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES EHMT2, BHMT2, BHMT GPR84 2967/4885FFAR1 4405/4885CA1 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.