SCHEMBL6632155

SCHEMBL6632155

c1ccc(-c2csc(-c3cncc(-c4scc(-c5ccccc5)c4-c4ccccc4)n3)c2-c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
RAB9A P51151 5/20 0.37
KDM4E B2RXH2 4/20 0.37
NPC1 O15118 3/20 0.37
CYP19A1 P11511 2/20 0.37
KMT2A Q03164 3/20 0.37
AR P10275 1/20 0.37
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
CYP3A4 P08684 1/20 0.35
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912908 0.83 ALOX5AP (0.38) ALDH1A1RAB9AKDM4ENPC1LMNA
SCHEMBL12912896 0.79 HPGDS (0.36) ALDH1A1RAB9AKDM4ENPC1KMT2A
SCHEMBL6036925 0.78 BACE1 (0.41) ALDH1A1KMT2AMAPTLMNAHPGD
SCHEMBL6741582 0.77 SMN1; SMN2 (0.51) ALDH1A1RAB9AKDM4ENPC1CYP19A1
SCHEMBL12860033 0.76 RAB9A (0.48) ALDH1A1RAB9AKDM4ENPC1KMT2A
Phosphine SCHEMBL28718427 0.76 BACE1 (0.41) ALDH1A1KMT2AMAPTLMNAHPGD
SCHEMBL12912887 0.74 BACE1 (0.40) ALDH1A1RAB9AKDM4ENPC1KMT2A
SCHEMBL12912909 0.73 CYP17A1 (0.46) ALDH1A1RAB9AKDM4ENPC1CYP19A1
SCHEMBL12912883 0.73 BACE1 (0.36) ALDH1A1KDM4EKMT2AMAPTLMNA
SCHEMBL24817308 0.72 ACHE (0.37) ALDH1A1KDM4EKMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291342-B1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KK (JP) 2014-06-04 EP disclosed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-8377574-B2 Dibenzo[c,g]fluorene compound and an organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US disclosed
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-02-24 US disclosed
WO-2009139499-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-11-19 WO disclosed
JP-2004339070-A THIOPHENE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME KOEI CHEM CO LTD 2004-12-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110042663-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME LEF1, GNG2, SCO2 ALDH1A1 271/4885RAB9A 579/4885KDM4E 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.