SCHEMBL12912947

SCHEMBL12912947

C[Si](C)(c1[nH]cc(-c2ccccc2)c1-c1ccccc1)c1scc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.34
LMNA P02545 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PARP1 P09874 1/20 0.32
GRM5 P41594 1/20 0.32
IMPDH2 P12268 1/20 0.31
LRRK2 Q5S007 2/20 0.31
AXL P30530 2/20 0.31
CDK8 P49336 1/20 0.31
TNIK Q9UKE5 1/20 0.31
MAPK1 P28482 2/20 0.30
PRKD3 O94806 2/20 0.30
MAP4K4 O95819 2/20 0.30
NTRK1 P04629 2/20 0.30
LCK P06239 2/20 0.30
CSF1R P07333 2/20 0.30
FGFR1 P11362 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912901 0.83 ALDH1A1 (0.40) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912922 0.83 CDK8 (0.41) PDPK1ALDH1A1PARP1GRM5LRRK2
SCHEMBL12912952 0.82 IMPDH2 (0.33) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912919 0.68 PARP1 (0.39) PDPK1ALDH1A1PARP1GRM5IMPDH2
SCHEMBL12912899 0.68 DAPK3 (0.36) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912921 0.68 PARP1 (0.40) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL27836567 0.67 CYP2A6 (0.47) LMNAALDH1A1GRM5LRRK2PRKD3
SCHEMBL12912951 0.66 PARP1 (0.34) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912954 0.66 PTGS2 (0.34) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912938 0.64 CYP2A6 (0.35) PDPK1LMNANPC1PARP1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed