Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891143 | 0.95 | LPL (0.55) | LPLLIPGSKP2OPRM1 | |
| SCHEMBL31516134 | 0.94 | LPL (0.56) | LPLLIPGOPRM1 | |
| SCHEMBL121471 | 0.94 | LPL (0.56) | LPLLIPGOPRM1 | |
| SCHEMBL15072065 | 0.94 | LPL (0.56) | LPLLIPGOPRM1 | |
| SCHEMBL12913231 | 0.84 | LIPG (0.45) | LPLLIPGNPC1 | |
| SCHEMBL21052188 | 0.83 | LPL (0.39) | LPLLIPG | |
| SCHEMBL27949745 | 0.80 | LPL (0.45) | LPLLIPGOPRM1 | |
| SCHEMBL25280699 | 0.79 | LPL (0.36) | LPLLIPGHTT | |
| SCHEMBL18966974 | 0.79 | LPL (0.41) | LPLLIPG | |
| SCHEMBL19176431 | 0.79 | LPL (0.41) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| EP-2209788-B1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | PPOX, PIN1, DDT | LPL 3369/4885LIPG 3850/4885SKP2 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.