Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.45 |
| ▸ | LPL | P06858 | 8/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049186 | 0.85 | LIPG (0.39) | LIPGLPLLTB4RANPEPLAP3 | |
| SCHEMBL12913268 | 0.84 | LPL (0.49) | LIPGLPLNPC1 | |
| SCHEMBL9891143 | 0.82 | LPL (0.55) | LIPGLPLHTR2ACYP1A2 | |
| SCHEMBL121471 | 0.81 | LPL (0.56) | LIPGLPLHTR2A | |
| SCHEMBL31516134 | 0.81 | LPL (0.56) | LIPGLPLHTR2A | |
| SCHEMBL15072065 | 0.81 | LPL (0.56) | LIPGLPLHTR2A | |
| SCHEMBL21052188 | 0.77 | LPL (0.39) | LIPGLPL | |
| SCHEMBL13764298 | 0.74 | LIPG (0.54) | LIPGLPLANPEPLAP3NPC1 | |
| SCHEMBL12913293 | 0.73 | LMNA (0.33) | LIPGLPL | |
| SCHEMBL20998175 | 0.71 | LIPG (0.50) | LIPGLPLANPEPLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| US-9018397-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2015-04-28 | — | — | US | disclosed |
| EP-2209788-B1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20130172575-A1 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404864-B2 | Pyrrolopyrrole derivatives, their manufacture and use | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | BASF SE (DE) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004004-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE | PPOX, PIN1, DDT | LIPG 3850/4885LPL 3369/4885LTB4R 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.