Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31292454 | 0.79 | RAB9A (0.43) | DGAT1CYP2C19SLC22A12 | |
| SCHEMBL129206 | 0.79 | RAB9A (0.43) | DGAT1CYP2C19SLC22A12 | |
| SCHEMBL1759981 | 0.78 | DGAT1 (0.41) | DGAT1CYP2C19SLC22A12 | |
| SCHEMBL3759061 | 0.78 | ALDH1A1 (0.48) | DGAT1CYP2C19SLC22A12 | |
| SCHEMBL131690 | 0.77 | PPARD (0.36) | DGAT1CYP2C19P4HTM | |
| SCHEMBL133858 | 0.76 | TGFBR1 (0.34) | CYP2C19 | |
| SCHEMBL15122279 | 0.76 | TRPV4 (0.32) | — | |
| SCHEMBL3180860 | 0.75 | KMT2A (0.49) | DGAT1SLC22A12 | |
| SCHEMBL31292214 | 0.74 | DGAT1 (0.39) | DGAT1CYP2C19 | |
| SCHEMBL38656034 | 0.73 | DGAT1 (0.43) | DGAT1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | DGAT1 2027/4885CYP2C19 44/4885MAP4K4 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.