Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309683 | 0.98 | PRKCA (0.43) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL1935917 | 0.97 | PRKCA (0.46) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL27983508 | 0.97 | PRKCA (0.46) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL4650754 | 0.97 | PRKCA (0.46) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL8192444 | 0.87 | LMNA (0.39) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL1133829 | 0.84 | ALDH1A1 (0.40) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL5061804 | 0.79 | BRD4 (0.33) | — | |
| SCHEMBL27689659 | 0.75 | ALDH1A1 (0.38) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL129229 | 0.75 | PTGS1 (0.53) | LMNAALDH1A1MAPTHPGDHSP90AA1 | |
| SCHEMBL7824143 | 0.74 | PRKCA (0.51) | PRKCALMNAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103997893-B | Pyrrolobenzodiazepines and targeting conjugates | 西雅图基因公司 | 2019-04-12 | — | — | CN | disclosed |