SCHEMBL12939244

SCHEMBL12939244

C1=Cc2c(c3ccccc3n2-c2ccccc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ ATM Q13315 1/20 0.48
▸ FOLH1 Q04609 1/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MAPK8 P45983 2/20 0.35
▸ IL1R1 P14778 1/20 0.35
▸ MAPK1 P28482 1/20 0.34
▸ PGR P06401 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MAPK9 P45984 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ KDR P35968 1/20 0.34
▸ SIGMAR1 Q99720 1/20 0.34
▸ LMNA P02545 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14050165 0.92 KDM4E (0.47) L3MBTL1KDM4EATM
SCHEMBL21779718 0.91 L3MBTL1 (0.40) L3MBTL1KDM4EATMFOLH1KMT2A
SCHEMBL20462315 0.91 KDM4E (0.38) L3MBTL1KDM4EATMFOLH1KDR
SCHEMBL12153423 0.91 L3MBTL1 (0.38) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL13190542 0.88 KDM4E (0.43) L3MBTL1KDM4EATMFOLH1
SCHEMBL23048270 0.88 ACHE (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12180924 0.88 KDM4E (0.36) L3MBTL1KDM4EATM
SCHEMBL257569 0.88 KDM4E (0.43) L3MBTL1KDM4EATM
SCHEMBL12325039 0.88 ACHE (0.41) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL12286336 0.88 HTR6 (0.38) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3150604-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-14 — — EP disclosed
US-20210013426-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2021-01-14 — — US disclosed
EP-2993215-B1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2019-06-19 — — EP disclosed
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 — — EP disclosed
US-20170309831-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
EP-3232485-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS UDC Ireland Limited (IE) 2017-10-18 — — EP disclosed
US-20170149007-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-05-25 — — US disclosed
US-8643268-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-02-04 — — US disclosed
US-20120248968-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2012-10-04 — — US disclosed
WO-2007132986-A1 SILICON TYPE COMPOUND HAVING BISPHENYLCARBAZOL IN MOLECULE AND METHOD FOR PREPARING ORGANIC THIN LAYER OF ORGANIC LIGHT EMITTING DEVICES USING THE SAME DONGJIN SEMICHEM CO., LTD (KR) 2007-11-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013426-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OR51E2 L3MBTL1 4661/4885KDM4E 4515/4885ATM 4238/4885
US-20170309831-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OR51E2 L3MBTL1 4661/4885KDM4E 4515/4885ATM 4238/4885
US-20170149007-A1 ORGANIC ELECTROLUMINESCENCE DEVICE EML4, EHD1, OR10J3 L3MBTL1 508/4885KDM4E 2535/4885ATM 1955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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