Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | OGT | O15294 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648483 | 0.84 | ALDH1A1 (0.43) | NPSR1BRD4MAOAMAOBCRBN | |
| SCHEMBL1294634 | 0.83 | CA9 (0.39) | NPSR1BRD4CA9HDAC3HDAC4 | |
| SCHEMBL12559768 | 0.77 | PKM (0.44) | BRD4CA9MAOAMAOBPKM | |
| SCHEMBL12559655 | 0.76 | CA9 (0.42) | BRD4CA9L3MBTL1PKM | |
| SCHEMBL11767335 | 0.75 | MAOA (0.50) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL1294298 | 0.75 | MAOB (0.50) | CA9MAOAMAOBRXRARXRB | |
| SCHEMBL13646686 | 0.73 | BRD4 (0.53) | BRD4CA9CRBNPKM | |
| SCHEMBL12559675 | 0.73 | L3MBTL1 (0.45) | BRD4CA9CRBNL3MBTL1PKM | |
| SCHEMBL1024704 | 0.73 | CRBN (0.43) | BRD4CA9OGTCRBNPOLB | |
| SCHEMBL1294840 | 0.71 | ALDH1A1 (0.42) | BRD4HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598434-B2 | Benzazepine compound | ASTELLAS PHARMA INC. (JP) | 2017-03-21 | — | — | US | disclosed |