Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25676047 | 0.80 | HDAC1 (0.54) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL8836113 | 0.79 | HDAC1 (0.53) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL243774 | 0.79 | ALDH1A1 (0.55) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL9006892 | 0.78 | ENPP3 (0.66) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL8748085 | 0.78 | ENPP3 (0.66) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL5945890 | 0.78 | ALDH1A1 (0.53) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL8836107 | 0.76 | HDAC1 (0.50) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL15762228 | 0.76 | HDAC1 (0.50) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL1051422 | 0.76 | HDAC1 (0.46) | HDAC1HDAC8HDAC6PDE4BNOTUM | |
| SCHEMBL5836945 | 0.75 | ENPP3 (0.54) | HDAC1HDAC8HDAC6PDE4BENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021531-A1 | OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK SHARP & DOHME CORP. | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021531-A1 | OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | FAAH, FAAH2, ALOX5 | HDAC1 715/4885HDAC8 714/4885HDAC6 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.