Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802436 | 0.88 | ESR1 (0.55) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL28492275 | 0.80 | ESR1 (0.63) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL1362192 | 0.78 | HPGD (0.68) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL4023960 | 0.78 | ESR1 (0.61) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL30523685 | 0.78 | HPGD (0.68) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL23276708 | 0.77 | ESR1 (0.59) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL2796509 | 0.77 | ESR1 (0.59) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL3649411 | 0.76 | ESR1 (0.53) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL8733751 | 0.75 | ESR1 (0.57) | ESR1ESR2TDP1GAATSHR | |
| SCHEMBL2127019 | 0.74 | GAA (0.68) | ESR1ESR2TDP1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422233-B2 | Vanilloid fatty hydroxamates as therapeutic anti-inflammatory pharmaceuticals | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-23 | — | — | US | disclosed |
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | FAAH, FAAH2, TRPV1 | ESR1 3492/4885ESR2 3193/4885ALOX5 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.