Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941324 | 0.86 | NAMPT (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL17202994 | 0.84 | TSHR (0.63) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14442106 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5637308 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28464045 | 0.79 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12964144 | 0.79 | MAPT (0.66) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8633952 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5636399 | 0.79 | RAB9A (0.72) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| Methyl Alcohol SCHEMBL27776732 | 0.78 | ALDH1A1 (0.97) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9422337 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173946-B2 | Bifunctional hydroxy-bisphosphonic acid derivatives | ATLANTHERA (FR) | 2015-11-03 | — | — | US | disclosed |
| US-9173946-B2 | Bifunctional hydroxy-bisphosphonic acid derivatives | ATLANTHERA (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20140086843-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | ATLANTHERA (FR) | 2014-03-27 | — | — | US | disclosed |
| US-20140086843-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | ATLANTHERA (FR) | 2014-03-27 | — | — | US | disclosed |
| WO-2012130911-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | ATLANTHERA (FR) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086843-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | BPGM, PHPT1, PTH1R | SMN1; SMN2 3824/4885ALDH1A1 1914/4885MEN1 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.