Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19571233 | 1.00 | MMP1 (0.46) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL2638976 | 0.89 | MMP9 (0.53) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL1359555 | 0.89 | MMP9 (0.53) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL1360010 | 0.89 | MMP9 (0.53) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL1358444 | 0.89 | MMP9 (0.53) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL2637880 | 0.88 | TBXAS1 (0.44) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL2637881 | 0.88 | TBXAS1 (0.44) | MMP1MMP2MMP3HDAC2MMP9 | |
| SCHEMBL8780188 | 0.87 | CETP (0.47) | MMP1MMP2CNR2 | |
| SCHEMBL4968691 | 0.87 | CETP (0.47) | MMP1MMP2CNR2 | |
| SCHEMBL18432775 | 0.87 | CETP (0.47) | MMP1MMP2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105131051-B | Synthetic glucopyranosyl lipid adjuvants | 传染性疾病研究院 | 2020-07-10 | — | — | CN | disclosed |
| US-9814772-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2017-11-14 | — | — | US | disclosed |
| EP-3124491-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS AND VACCINE COMPOSITIONS CONTAINING THEM | Infectious Disease Research Institute (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2437753-B1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS AND VACCINE COMPOSITIONS CONTAINING THEM | INFECTIOUS DISEASE RES INST (US) | 2016-08-31 | — | — | EP | disclosed |
| US-8722064-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2014-05-13 | — | — | US | disclosed |
| WO-2010141861-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100310602-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310602-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | MMP1 4673/4885MMP2 3071/4885MMP3 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.