Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 5/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359555 | 1.00 | MMP9 (0.53) | MMP9MMP1MMP2FFAR1HDAC2 | |
| SCHEMBL1358444 | 1.00 | MMP9 (0.53) | MMP9MMP1MMP2FFAR1HDAC2 | |
| SCHEMBL2638976 | 1.00 | MMP9 (0.53) | MMP9MMP1MMP2FFAR1HDAC2 | |
| SCHEMBL12972769 | 0.89 | MMP1 (0.46) | MMP9MMP1MMP2HDAC2HDAC3 | |
| SCHEMBL2637880 | 0.89 | TBXAS1 (0.44) | MMP9MMP1MMP2FFAR1HDAC2 | |
| SCHEMBL2637881 | 0.89 | TBXAS1 (0.44) | MMP9MMP1MMP2FFAR1HDAC2 | |
| SCHEMBL19571233 | 0.89 | MMP1 (0.46) | MMP9MMP1MMP2HDAC2HDAC3 | |
| SCHEMBL1358863 | 0.87 | MMP2 (0.50) | MMP9MMP1MMP2MMP3 | |
| SCHEMBL1358859 | 0.87 | MMP2 (0.50) | MMP9MMP1MMP2MMP3 | |
| SCHEMBL1359365 | 0.87 | MMP2 (0.50) | MMP9MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309276-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140011987-A1 | Synthetic Lipid A Derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-01-09 | — | — | US | disclosed |
| US-8563523-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2011-11-17 | — | — | US | disclosed |
| US-7833993-B2 | Immunomodulatory compounds and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2010-09-02 | — | — | US | disclosed |
| EP-1439184-B1 | Immunological adjuvant compounds | EISAI R&D MAN CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-7560584-B2 | Immunomodulatory compounds and methods of use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011987-A1 | Synthetic Lipid A Derivative | DDOST, STT3A, UGCG | MMP9 4782/4885MMP1 4857/4885MMP2 4383/4885 |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | MMP9 4782/4885MMP1 4857/4885MMP2 4383/4885 |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | MMP9 4782/4885MMP1 4857/4885MMP2 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.