Phenylglyoxal

Phenylglyoxal

SCHEMBL1297396

CCOCC(=O)c1ccccc1OCC.O=CC(=O)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GLA P06280 1/20 0.46
HCRTR1 O43613 2/20 0.45
MAPT P10636 5/20 0.45
ATM Q13315 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
LMNA P02545 2/20 0.43
ABCB1 P08183 1/20 0.43
NPC1 O15118 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350014 0.86 HCRTR1 (0.57) KMT2AMEN1ALDH1A1MAPK1L3MBTL1
SCHEMBL333676 0.86 HCRTR1 (0.57) KMT2AMEN1ALDH1A1MAPK1L3MBTL1
SCHEMBL11601663 0.79 HCRTR1 (0.58) KMT2AMEN1RAB9AALDH1A1MAPK1
Phenylglyoxal SCHEMBL8060257 0.79 MAPK1 (0.69) KMT2AMEN1RAB9AALDH1A1MAPK1
SCHEMBL720460 0.76 RAB9A (0.67) KMT2AMEN1RAB9AALDH1A1MAPK1
SCHEMBL30033997 0.76 RAB9A (0.67) KMT2AMEN1RAB9AALDH1A1MAPK1
SCHEMBL29483366 0.75 NPC1 (0.71) KMT2AMEN1RAB9AALDH1A1MAPK1
SCHEMBL7631355 0.75 NPC1 (0.71) KMT2AMEN1RAB9AALDH1A1MAPK1
Hydrochloric Acid SCHEMBL8729799 0.74 RAB9A (0.65) KMT2AMEN1RAB9AALDH1A1MAPK1
Bicarbonate SCHEMBL27740096 0.74 RAB9A (0.65) KMT2AMEN1RAB9AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563896-A2 DELIVERY PARTICLES The Procter & Gamble Company (US) 2013-03-06 EP claimed
US-8071214-B2 Particle with selected permeance wall APPLETON PAPERS INC. (US) 2011-12-06 US claimed
US-20110268778-A1 DELIVERY PARTICLES THE PROCTER & GAMBLE COMPANY 2011-11-03 US claimed
WO-2010079466-A2 DELIVERY PARTICLES THE PROCTER & GAMBLE COMPANY (US) 2010-07-15 WO claimed
WO-2009134234-A1 PARTICLE WITH SELECTED PERMEANCE WALL APPLETON PAPERS INC. (US) 2009-11-05 WO claimed
US-20090274907-A1 Particle with selected permeance wall APPLETON PAPERS INC. (US) 2009-11-05 US claimed
US-11931711-B2 Microcapsule clusters ENCAPSYS, LLC (US) 2024-03-19 US disclosed
US-20230264161-A1 Microcapsule Clusters ENCAPSYS LLC (US) 2023-08-24 US disclosed
EP-3946710-A1 MICROCAPSULE CLUSTERS Encapsys, LLC (US) 2022-02-09 EP disclosed
CN-113710357-A Method for preparing polymer capsules 宝洁公司 2021-11-26 CN disclosed
US-11180714-B2 Controlled release microcapsules ENCAPSYS, LLC (US) 2021-11-23 US disclosed
CN-113660929-A Polymer capsules 宝洁公司 2021-11-16 CN disclosed
CN-113631249-A Device and method for producing an emulsion 宝洁公司 2021-11-09 CN disclosed
US-9714396-B2 Controlled release dual walled microcapsules ENCAPSYS LLC (US) 2017-07-25 US disclosed
US-9714397-B2 Controlled release microcapsules ENCAPSYS LLC (US) 2017-07-25 US disclosed
US-20160108340-A1 CONTROLLED RELEASE MICROCAPSULES ENCAPSYS LLC (US) 2016-04-21 US disclosed
EP-2563896-A2 DELIVERY PARTICLES The Procter & Gamble Company (US) 2013-03-06 EP disclosed
US-8071214-B2 Particle with selected permeance wall APPLETON PAPERS INC. (US) 2011-12-06 US disclosed
US-20110268778-A1 DELIVERY PARTICLES THE PROCTER & GAMBLE COMPANY 2011-11-03 US disclosed
WO-2010079466-A2 DELIVERY PARTICLES THE PROCTER & GAMBLE COMPANY (US) 2010-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110268778-A1 DELIVERY PARTICLES LIPA, CHMP4B, ABCB4 KMT2A 4783/4885MEN1 1316/4885RAB9A 2217/4885
US-11180714-B2 Controlled release microcapsules NSF, CRH, CHMP4B KMT2A 4847/4885MEN1 208/4885RAB9A 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.