Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985393 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL18803710 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL10657344 | 0.87 | CTSL (0.50) | HPGDALDH1A1RAB9AHTTCTSS | |
| SCHEMBL10657345 | 0.87 | CTSL (0.50) | HPGDALDH1A1RAB9AHTTCTSS | |
| SCHEMBL12983994 | 0.85 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL12983996 | 0.85 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5210394 | 0.83 | CA2 (0.49) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5118660 | 0.83 | CA2 (0.49) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL13370243 | 0.82 | CA2 (0.65) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL12947926 | 0.82 | TAS1R3 (0.58) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514402-B1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEM IND INC (JP) | 2016-08-31 | — | — | EP | claimed |
| US-9414998-B2 | Preventing or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2016-08-16 | — | — | US | claimed |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-30 | — | — | US | claimed |
| EP-2514402-A1 | PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION | Pola Chemical Industries Inc. (JP) | 2012-10-24 | — | — | EP | claimed |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-10-11 | — | — | US | claimed |
| EP-4234042-B1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEM IND INC (JP) | 2025-08-13 | — | — | EP | disclosed |
| EP-4234042-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | Pola Chemical Industries, Inc. (JP) | 2023-08-30 | — | — | EP | disclosed |
| EP-3708148-B1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEM IND INC (JP) | 2023-07-19 | — | — | EP | disclosed |
| EP-3708148-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | Pola Chemical Industries Inc. (JP) | 2020-09-16 | — | — | EP | disclosed |
| US-10568822-B2 | Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2020-02-25 | — | — | US | disclosed |
| EP-3536306-A2 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | Pola Chemical Industries Inc. (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3127533-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | Pola Chemical Industries Inc. (JP) | 2017-02-08 | — | — | EP | disclosed |
| EP-2514402-B1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEM IND INC (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-9414998-B2 | Preventing or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-2514402-A1 | PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION | Pola Chemical Industries Inc. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | MC1R, TYR, NAMPT | SMN1; SMN2 4699/4885MEN1 2367/4885KMT2A 632/4885 |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | SMN1; SMN2 937/4885MEN1 2910/4885KMT2A 1630/4885 |
| US-10568822-B2 | Melanogenesis inhibitor comprising d-pantothenyl alcohol, and skin-whitening cosmetic containing same melanogenesis inhibitor | MC1R, TYR, NAMPT | SMN1; SMN2 4699/4885MEN1 2367/4885KMT2A 632/4885 |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | SMN1; SMN2 937/4885MEN1 2910/4885KMT2A 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.