Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191348 | 0.91 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986941 | 0.90 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986562 | 0.84 | MAPT (0.58) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL29367989 | 0.83 | MAPT (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986381 | 0.82 | MAPT (0.71) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986716 | 0.81 | EGFR (0.62) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986680 | 0.80 | KDR (0.65) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12985974 | 0.80 | EGFR (0.61) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986712 | 0.79 | EGFR (0.64) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12986672 | 0.79 | EGFR (0.60) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012136910-A1 | DERIVATIVES OF 4-ARYLCOUMARIN AND 4-ARYLQUINOLINE, THERAPEUTIC USES THEREOF AND METHOD FOR SYNTHESISING SAME | UNIVERSITÉ DE MARSEILLE (FR) | 2012-10-11 | — | — | WO | claimed |
| WO-2012136910-A1 | DERIVATIVES OF 4-ARYLCOUMARIN AND 4-ARYLQUINOLINE, THERAPEUTIC USES THEREOF AND METHOD FOR SYNTHESISING SAME | UNIVERSITÉ DE MARSEILLE (FR) | 2012-10-11 | — | — | WO | disclosed |