SCHEMBL29367989

SCHEMBL29367989

COc1ccc(-c2cc(=O)oc3cc(O)cc(OC)c23)cc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.60
▸ CYP1B1 Q16678 4/20 0.59
▸ CYP1A1 P04798 3/20 0.59
▸ CYP1A2 P05177 2/20 0.59
▸ XDH P47989 2/20 0.59
▸ KDM1A O60341 1/20 0.59
▸ ABCC1 P33527 1/20 0.59
▸ IPMK Q8NFU5 1/20 0.59
▸ HDAC6 Q9UBN7 1/20 0.59
▸ IP6K2 Q9UHH9 1/20 0.59
▸ TUBB4A P04350 1/20 0.57
▸ TUBB P07437 1/20 0.57
▸ TUBA3C P0DPH7 1/20 0.57
▸ TUBA1B P68363 1/20 0.57
▸ TUBA4A P68366 1/20 0.57
▸ TUBB4B P68371 1/20 0.57
▸ TUBB3 Q13509 1/20 0.57
▸ TUBB2A Q13885 1/20 0.57
▸ TUBB8 Q3ZCM7 1/20 0.57
▸ TUBA3E Q6PEY2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12986381 0.89 MAPT (0.71) MAPTXDHABCC1ALDH1A1HPGD
SCHEMBL12986562 0.86 MAPT (0.58) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL12986941 0.84 ALDH1A1 (0.76) MAPTCYP1B1CYP1A1ALDH1A1HPGD
SCHEMBL12986397 0.83 ALDH1A1 (0.60) MAPTCYP1B1CYP1A1TUBB4ATUBB
SCHEMBL12986716 0.80 EGFR (0.62) MAPTCYP1B1CYP1A1CYP1A2XDH
SCHEMBL12986680 0.79 KDR (0.65) MAPTCYP1B1CYP1A1CYP1A2TUBB4A
SCHEMBL12986712 0.78 EGFR (0.64) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30677926 0.76 MAP1LC3B (0.68) MAPTCYP1B1CYP1A1CYP1A2KDM1A
SCHEMBL29115331 0.76 MAP1LC3B (0.68) MAPTCYP1B1CYP1A1CYP1A2KDM1A
SCHEMBL12985974 0.76 EGFR (0.61) MAPTCYP1A2ALDH1A1HPGDEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137678-A1 METHODS FOR TREATING OR PREVENTING NEUROENDOCRINE TUMOR FORMATION USING XPO1 INHIBITORS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-05-21 — — US disclosed
WO-2026098924-A1 PROCESSING DEVICE INCLUDING A TRAM MEMORY FOTONATION LIMITED (IE) 2026-05-15 — — WO disclosed
US-12519564-B2 Systems and methods for dual list decoding of convolutional codes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-06 — — US disclosed
US-20250336063-A1 Multimodal Deep Learning to Differentiate Tumor Recurrence from Treatment Effect in Human Glioblastoma UNIV VIRGINIA PATENT FOUNDATION (US) 2025-10-30 — — US disclosed
US-20250310030-A1 Systems and Methods for Dual List Decoding of Convolutional Codes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-10-02 — — US disclosed
EP-4619373-A1 METHOD FOR MANUFACTURING SYNTHETIC VANILLIN Deasyl SA (CH) 2025-09-24 — — EP disclosed
US-12377103-B2 Use of bromodomain-containing protein 9 inhibitors to treat and/or prevent uterine leiomyosarcoma THE UNIVERSITY OF CHICAGO (US) 2025-08-05 — — US disclosed
WO-2025057018-A1 EXPRESSION VECTOR FOR RECOMBINANT U-CONOTOXIN THIA OR TIIIALAMUT EXPRESSION IN E.COLI Science4Beauty Sp. z o.o. (PL) 2025-03-20 — — WO disclosed
US-20250082823-A1 IMPLANT AND COATING TO REDUCE OSTEOLYSIS Sanford Burnham Prebys Medical Discovery Institute 2025-03-13 — — US disclosed
CN-111684343-B Optical method and apparatus 牛津大学科技创新有限公司 2025-02-21 — — CN disclosed
WO-2022234128-A1 APPARATUS AND METHOD BASED ON MEMRISTIVE COMPUTING PARADIGMS THAT ARE BASED ON A DOMINO PROCESSING UNIT Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-11-10 — — WO disclosed
US-11495326-B2 Metagenomic library and natural product discovery platform ZYMERGEN INC. (US) 2022-11-08 — — US disclosed
CN-105283547-B Recombinant host cells for biosynthetic production 罗地亚经营管理公司 2022-10-04 — — CN disclosed
CN-109414487-B Compositions and methods utilizing STAT1/3 inhibitors with oncolytic herpes viruses 复诺健生物科技加拿大有限公司 2022-09-02 — — CN disclosed
US-20220184197-A1 MULTI-SUBUNIT VACCINES TO ELICIT BOTH MHC- AND CD1-RESTRICTED T CELL RESPONSES NORTHWESTERN UNIVERSITY 2022-06-16 — — US disclosed
CN-114432327-A Application of flavonoid carbon glycoside compound in preparation of medicine for preventing or treating acute lung injury and/or acute respiratory distress syndrome 苏州凯祥生物科技有限公司 2022-05-06 — — CN disclosed
WO-2022081992-A1 METHODS FOR SUPPORTING GRAIN INTENSIVE DIETS IN RUMINANTS WITH ADMINISTRATION OF CHORDICOCCUS SP. NATIVE MICROBIALS, INC. (US) 2022-04-21 — — WO disclosed
CN-114365747-A Antifungal methylobacterium compositions and methods of use 新叶共生有限公司 2022-04-19 — — CN disclosed
EP-3545657-B1 SYSTEMS AND METHODS FOR DECODING OF MODULATED SYMBOLS OR COMPENSATING CHANNEL FREQUENCY RESPONSE OF THE MODULATED SYMBOLS HUAWEI TECH CO LTD (CN) 2022-04-13 — — EP disclosed
CN-108037481-B Robustness gradable sparse array frequency and DOA estimation method and device 天津大学 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12377103-B2 Use of bromodomain-containing protein 9 inhibitors to treat and/or prevent uterine leiomyosarcoma BRD9, BRDT, BRD2 MAPT 4268/4885CYP1B1 4422/4885CYP1A1 4798/4885
US-20260137678-A1 METHODS FOR TREATING OR PREVENTING NEUROENDOCRINE TUMOR FORMATION USING XPO1 INHIBITORS RB1, ERCC4, TP53 MAPT 3076/4885CYP1B1 3125/4885CYP1A1 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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