SCHEMBL12994643

SCHEMBL12994643

C/N=C(/c1ccc(OCCCOc2ccc(/C(=N/C)C(F)(F)C(F)(F)C(F)(F)F)cc2)cc1)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMPRSS2 O15393 2/20 0.44
PRSS1 P07477 7/20 0.42
FURIN P09958 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
PRMT1 Q99873 3/20 0.39
F2 P00734 2/20 0.39
ST14 Q9Y5Y6 2/20 0.39
GAA P10253 2/20 0.39
PLAU P00749 1/20 0.39
PRMT5 O14744 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
PTP4A3 O75365 1/20 0.39
SLC22A3 O75751 1/20 0.39
F10 P00742 1/20 0.39
PLG P00747 1/20 0.39
S100B P04271 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11991281 1.00 TMPRSS2 (0.44) TMPRSS2PRSS1FURINL3MBTL1PRMT1
SCHEMBL10239160 0.89 PRSS1 (0.33) TMPRSS2PRSS1L3MBTL1PRMT1F2
SCHEMBL12994641 0.84 FURIN (0.45) TMPRSS2PRSS1FURINL3MBTL1PRMT1
SCHEMBL11991282 0.84 FURIN (0.45) TMPRSS2PRSS1FURINL3MBTL1PRMT1
SCHEMBL10150737 0.83 ALDH1A1 (0.36) GAA
SCHEMBL12994622 0.83 LMNA (0.46) PRSS1GAAADRA1A
SCHEMBL10239151 0.83 LMNA (0.46) PRSS1GAAADRA1A
SCHEMBL10187218 0.79 PARP15 (0.44)
SCHEMBL12994629 0.79 PARP10 (0.40) RAB9A
SCHEMBL10239156 0.79 PARP10 (0.40) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283106-B2 Sulfonic acid salt and derivative thereof, photoacid generator agent, and resist material and pattern formation method using the photoacid generator agent CENTRAL GLASS COMPANY, LIMITED (JP) 2012-10-09 US disclosed
US-20100304303-A1 Novel Sulfonic Acid Salt and Derivative Thereof, Photoacid Generator Agent, and Resist Material and Pattern Formation Method Using the Photoacid Generator Agent CENTRAL GLASS COMPANY, LIMITED (JP) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304303-A1 Novel Sulfonic Acid Salt and Derivative Thereof, Photoacid Generator Agent, and Resist Material and Pattern Formation Method Using the Photoacid Generator Agent ARF1, ARF5, ARF6 TMPRSS2 2797/4885PRSS1 511/4885FURIN 1661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.