Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023657 | 0.85 | PLK1 (0.50) | LMNAALDH1A1MAPK1MAPTNPC1 | |
| SCHEMBL12997232 | 0.84 | HDAC3 (0.50) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL29798859 | 0.83 | NPC1 (0.58) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL17978853 | 0.83 | NPC1 (0.48) | ALDH1A1MAPK1TSHRMAPTNPC1 | |
| SCHEMBL3705474 | 0.80 | RAB9A (0.67) | LMNAALDH1A1MAPK1SLC22A2SLC22A1 | |
| SCHEMBL18259815 | 0.78 | NPC1 (0.52) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL1290599 | 0.77 | LMNA (0.68) | LMNAALDH1A1MAPK1SLC22A2SLC22A1 | |
| SCHEMBL18259868 | 0.77 | POLB (0.61) | ALDH1A1MAPK1TSHRMAPTNPC1 | |
| SCHEMBL9344489 | 0.77 | KDM4E (0.68) | LMNAALDH1A1MAPK1SLC22A2SLC22A1 | |
| Hydrochloric Acid SCHEMBL5921713 | 0.76 | LMNA (0.69) | LMNAALDH1A1MAPK1SLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130230898-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-09-05 | — | — | US | disclosed |
| US-20130230898-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-09-05 | — | — | US | disclosed |
| US-8404834-B2 | Hydroxyalkyl starch derivatives and process for their preparation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404834-B2 | Hydroxyalkyl starch derivatives and process for their preparation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-03-26 | — | — | US | disclosed |
| EP-2231711-B1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| WO-2009077154-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070950-A1 | Hydroxyalkyl starch derivatives and process for their preparation | Fresenius Kabi Deutschland GmbH (DE) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | HDHD5, KHK, SORD | LMNA 1787/4885ALDH1A1 1604/4885MAPK1 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.