Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997291 | 0.81 | — | — | |
| Fluoride SCHEMBL1995827 | 0.71 | OPRM1 (0.48) | PLA2G1BPLA2G2AOPRM1S1PR2S1PR1 | |
| SCHEMBL12997262 | 0.70 | ALDH1A1 (0.30) | — | |
| SCHEMBL10824704 | 0.69 | PLA2G1B (0.41) | PLA2G1BPLA2G2AOPRM1S1PR2S1PR1 | |
| SCHEMBL272998 | 0.68 | OPRM1 (0.50) | PLA2G1BPLA2G2AOPRM1S1PR2S1PR1 | |
| SCHEMBL12997261 | 0.67 | — | — | |
| SCHEMBL10914883 | 0.67 | OPRM1 (0.41) | PLA2G1BPLA2G2AOPRM1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL1997517 | 0.66 | OPRM1 (0.48) | PLA2G1BPLA2G2AOPRM1S1PR2S1PR1 | |
| Bromide SCHEMBL1993996 | 0.66 | OPRM1 (0.48) | PLA2G1BPLA2G2AOPRM1S1PR2S1PR1 | |
| SCHEMBL23211228 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130230898-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-09-05 | — | — | US | disclosed |
| US-20130230898-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-09-05 | — | — | US | disclosed |
| US-8404834-B2 | Hydroxyalkyl starch derivatives and process for their preparation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404834-B2 | Hydroxyalkyl starch derivatives and process for their preparation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-03-26 | — | — | US | disclosed |
| EP-2231711-B1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| WO-2009077154-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070950-A1 | Hydroxyalkyl starch derivatives and process for their preparation | Fresenius Kabi Deutschland GmbH (DE) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305033-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | HDHD5, KHK, SORD | PLA2G1B 4142/4885PLA2G2A 4081/4885OPRM1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.