Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.48 |
| ▸ | S1PR2 known ✓ | O95136 | 5/20 | 0.46 |
| ▸ | S1PR1 known ✓ | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 known ✓ | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR4 known ✓ | O95977 | 4/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272998 | 0.97 | OPRM1 (0.50) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL15577381 | 0.94 | ALDH1A1 (0.50) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL21807740 | 0.94 | OPRM1 (0.57) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL6264548 | 0.94 | ALDH1A1 (0.50) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Fluoride SCHEMBL1995827 | 0.93 | OPRM1 (0.48) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Bromide SCHEMBL1993996 | 0.93 | OPRM1 (0.48) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL21807741 | 0.91 | PLA2G1B (0.58) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| Hydrochloric Acid SCHEMBL8773734 | 0.91 | PLA2G1B (0.58) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL6764723 | 0.90 | ALDH1A1 (0.52) | OPRM1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL13971145 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243013-B2 | Ionic compound, method for producing the same, and ion-conductive material comprising the same | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-01-26 | — | — | US | disclosed |
| CN-104387410-A | Method for producing ionic compound | NIPPON CATALYTIC CHEM IND | 2015-03-04 | — | — | CN | disclosed |
| CN-102124014-A | Ionic compound, method for producing same, and ion-conductive material using same | NIPPON CATALYTIC CHEM IND | 2011-07-13 | — | — | CN | disclosed |
| US-20110150736-A1 | IONIC COMPOUND, METHOD FOR PRODUCING THE SAME, AND ION-CONDUCTIVE MATERIAL COMPRISING THE SAME | NIPPON SHOKUBAI CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2327707-A1 | IONIC COMPOUND, PROCESS FOR PRODUCING SAME, AND ION-CONDUCTIVE MATERIAL COMPRISING SAME | Nippon Shokubai Co., Ltd. (JP) | 2011-06-01 | — | — | EP | disclosed |
| EP-1066329-B1 | POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1135375-B1 | SUBSTITUTED 1,3,5-TRIAZINES AS HERBICIDES | BAYER CROPSCIENCE KK (JP) | 2005-11-09 | — | — | EP | disclosed |
| CN-1165528-C | Substituted 1,3,5-triazines as herbicides | �ձ��ݶ�ũҩ��ʽ���� | 2004-09-08 | — | — | CN | disclosed |
| US-6645915-B1 | Cyclohexylalkylamino-1,3,5-triazines derivatives; herbicides; cyclization of biguanide | NIHON BAYER AGROCHEM K. K. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6426313-B2 | CROSSLINKED POLYMERIC BEADS AS CATALYST SUPPORT | EXXON MOBIL CHEMICAL PATENTS INC. | 2002-07-30 | — | — | US | disclosed |
| US-20020010079-A1 | POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-01-24 | — | — | US | disclosed |
| CN-1329602-A | Substituted 1,3,5-triazines as herbicides | BAYER AGROCHEM KK (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-1135375-A2 | SUBSTITUTED 1,3,5-TRIAZINES AS HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032580-A2 | SUBSTITUTED 1,3,5-TRIAZINES AS HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150736-A1 | IONIC COMPOUND, METHOD FOR PRODUCING THE SAME, AND ION-CONDUCTIVE MATERIAL COMPRISING THE SAME | KCNB1, KCNB2, KCNMB1 | OPRM1 2319/4885S1PR2 2809/4885S1PR1 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.