Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820359 | 0.92 | RAB9A (0.46) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL28255183 | 0.91 | TSHR (0.54) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL17481130 | 0.90 | HDAC2 (0.49) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19051491 | 0.87 | RAB9A (0.55) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL10248027 | 0.87 | HPGDS (0.54) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13211909 | 0.86 | NPC1 (0.56) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1299965 | 0.86 | KMT2A (0.47) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL12459934 | 0.86 | ESRRG (0.49) | MAPTRAB9ANPC1SMN1; SMN2ESRRG | |
| SCHEMBL1300384 | 0.86 | NPC1 (0.52) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL18381247 | 0.85 | KMT2A (0.60) | MAPTRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003395-B2 | Non-signal imidazole reagents for mass spectrometry analysis of phosphomonoesters | TRACE BIO ANALYTICS, LLC (US) | 2011-08-23 | — | — | US | claimed |
| US-20090215185-A1 | Non-signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | Trace Bio Analytics, Inc. | 2009-08-27 | — | — | US | claimed |
| WO-2007002135-A9 | NON-SIGNAL IMIDAZOLE REAGENTS FOR MASS SPECTROMETRY ANALYSIS OF PHOSPHOMONOESTERS | TRACE BIO ANALYTICS LLC (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2007002135-A2 | NON-SIGNAL IMIDAZOLE REAGENTS FOR MASS SPECTROMETRY ANALYSIS OF PHOSPHOMONOESTERS | TRACE BIO ANALYTICS, LLC (US) | 2007-01-04 | — | — | WO | claimed |
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | MILLENNIUM PHARM INC (US) | 2025-02-06 | — | — | US | disclosed |
| US-20110269968-A1 | Non-Signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | Trace Bio Analytics, Inc. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269968-A1 | Non-Signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | Trace Bio Analytics, Inc. (US) | 2011-11-03 | — | — | US | disclosed |
| US-8003395-B2 | Non-signal imidazole reagents for mass spectrometry analysis of phosphomonoesters | TRACE BIO ANALYTICS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003395-B2 | Non-signal imidazole reagents for mass spectrometry analysis of phosphomonoesters | TRACE BIO ANALYTICS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100255607-A1 | AFFINITY CONTROL OF TAGGING NOISE | NORTHEASTERN UNIVERSITY | 2010-10-07 | — | — | US | disclosed |
| US-20090215185-A1 | Non-signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | Trace Bio Analytics, Inc. | 2009-08-27 | — | — | US | disclosed |
| US-20090215185-A1 | Non-signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | Trace Bio Analytics, Inc. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | WNT1, XPOT, CTNNBL1 | MAPT 458/4885RAB9A 3071/4885NPC1 2556/4885 |
| US-20110269968-A1 | Non-Signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | PPIP5K2, PHPT1, IP6K3 | MAPT 3122/4885RAB9A 3998/4885NPC1 4772/4885 |
| US-20090215185-A1 | Non-signal Imidazole Reagents for Mass Spectrometry Analysis of Phosphomonoesters | PPIP5K2, PHPT1, IP6K3 | MAPT 3088/4885RAB9A 3996/4885NPC1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.