Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005293 | 0.94 | ALDH1A1 (0.33) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL16479409 | 0.88 | ESR1 (0.34) | ALDH1A1TSHRNPSR1KMT2AMEN1 | |
| SCHEMBL16474343 | 0.88 | ALDH1A1 (0.34) | ALDH1A1TSHRNPSR1KMT2AMEN1 | |
| SCHEMBL18971681 | 0.87 | SIRT2 (0.34) | ALDH1A1NPSR1KMT2AMEN1CYP3A4 | |
| SCHEMBL13005284 | 0.86 | ESR1 (0.34) | ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL13005290 | 0.85 | SIRT2 (0.34) | — | |
| SCHEMBL13005294 | 0.85 | DHODH (0.35) | ALDH1A1TSHRNPSR1KMT2AMEN1 | |
| SCHEMBL15693690 | 0.85 | DHODH (0.35) | ALDH1A1TSHRNPSR1KMT2AMEN1 | |
| SCHEMBL15693594 | 0.84 | NR4A2 (0.34) | ALDH1A1TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL7784131 | 0.83 | MAPT (0.39) | ALDH1A1TSHRNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | ALDH1A1 1833/4885TSHR 548/4885NPSR1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.