Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005291 | 0.86 | ALDH1A1 (0.33) | ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL16474343 | 0.86 | ALDH1A1 (0.34) | ESR1ESR2KDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL16479409 | 0.86 | ESR1 (0.34) | ESR1ESR2KDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL15693690 | 0.83 | DHODH (0.35) | KDM4EALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL15693594 | 0.82 | NR4A2 (0.34) | KDM4EALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL7784131 | 0.81 | MAPT (0.39) | KDM4EALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL13005293 | 0.80 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPT | |
| SCHEMBL13005279 | 0.79 | S1PR1 (0.35) | MAPT | |
| SCHEMBL16474355 | 0.79 | LMNA (0.38) | KDM4EALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL16479408 | 0.79 | METAP1 (0.35) | ESR1ESR2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324296-A1 | DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES | NR0B2, NR0B1, NR2E3 | ESR1 2266/4885ESR2 983/4885KDM4E 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.