Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005491 | 0.93 | CTRB1 (0.51) | MMEMMEL1HDAC4HDAC6CTRB1 | |
| SCHEMBL13005579 | 0.90 | KMT2A (0.47) | MMEMMEL1HPGDSCTRB1UTS2R | |
| SCHEMBL13005436 | 0.90 | HDAC4 (0.45) | MMEMMEL1HDAC4HPGDSALDH1A1 | |
| SCHEMBL13060697 | 0.90 | MME (0.52) | MMEMMEL1HDAC4HDAC6HPGDS | |
| SCHEMBL13005434 | 0.90 | HDAC4 (0.45) | MMEMMEL1HDAC4HPGDSALDH1A1 | |
| SCHEMBL13005497 | 0.87 | F2 (0.41) | MMEMMEL1HDAC4HDAC6HPGDS | |
| SCHEMBL13005455 | 0.86 | HPGDS (0.45) | HPGDSALDH1A1UTS2RCTSLCTSS | |
| SCHEMBL13005431 | 0.84 | HPGDS (0.43) | HDAC4HPGDSALDH1A1UTS2RCTSL | |
| SCHEMBL13005424 | 0.84 | HPGDS (0.43) | HDAC4HPGDSALDH1A1UTS2RCTSL | |
| SCHEMBL13005584 | 0.83 | KMT2A (0.51) | HDAC4HDAC6CTRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |