Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060860 | 0.89 | BCL2 (0.42) | HPGDSUTS2RMMEMMEL1 | |
| SCHEMBL13005436 | 0.88 | HDAC4 (0.45) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005434 | 0.88 | HDAC4 (0.45) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005665 | 0.87 | MME (0.51) | HPGDSUTS2RMMEMMEL1HDAC4 | |
| SCHEMBL13005455 | 0.84 | HPGDS (0.45) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005579 | 0.84 | KMT2A (0.47) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005424 | 0.82 | HPGDS (0.43) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005431 | 0.82 | HPGDS (0.43) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005671 | 0.81 | F2 (0.45) | F2F10PRSS1HPGDSUTS2R | |
| SCHEMBL13005620 | 0.81 | ROCK2 (0.38) | UTS2RCTSLCTSSCTSKPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |