Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14277382 | 0.77 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL11855121 | 0.71 | — | — | |
| SCHEMBL2362804 | 0.70 | ALDH1A1 (0.39) | ALDH1A1GAA | |
| SCHEMBL10818200 | 0.69 | TSHR (0.46) | ALDH1A1TSHRSMN1; SMN2MAPTPOLB | |
| SCHEMBL13544528 | 0.68 | TSHR (0.42) | ALDH1A1TSHRSMN1; SMN2MAPTPOLB | |
| SCHEMBL20734581 | 0.68 | ALDH1A1 (0.54) | ALDH1A1TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL760267 | 0.66 | ALDH1A1 (0.52) | ALDH1A1TSHR | |
| SCHEMBL692168 | 0.66 | — | — | |
| SCHEMBL12622560 | 0.65 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL20734640 | 0.64 | KDM4A (0.67) | ALDH1A1TSHRSMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851582-B2 | S-(α, α′-disubstituted-α″-acetic acid)—substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7498456-B2 | S-(α, α′-disubstituted-α″-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerization, process and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080214773-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) - Substituted Dithiocarbonate Derivatives For Controlled Radical Polymerizations, Process and Polymers Made Therefrom | LAI JOHN TA-YUAN | 2008-09-04 | — | — | US | disclosed |
| US-20070167571-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) Substituted Dithiocarbonate Derivatives for Controlled Radical Polymerizations, Process and Polymers Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2007-07-19 | — | — | US | disclosed |
| US-7205368-B2 | S-(α, α′-disubstituted-α′ ′-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom | NOVEON, INC. (US) | 2007-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214773-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) - Substituted Dithiocarbonate Derivatives For Controlled Radical Polymerizations, Process and Polymers Made Therefrom | TST, ACMSD, ETFA | ALDH1A1 110/4885TSHR 2886/4885SMN1; SMN2 2111/4885 |
| US-20070167571-A1 | S-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) Substituted Dithiocarbonate Derivatives for Controlled Radical Polymerizations, Process and Polymers Made Therefrom | TST, ACMSD, SRM | ALDH1A1 131/4885TSHR 3041/4885SMN1; SMN2 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.