Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | AGER | Q15109 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490806 | 0.91 | HTT (0.60) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14490855 | 0.89 | AGER (0.60) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7410882 | 0.88 | HTT (0.57) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL133355 | 0.88 | AGER (0.58) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6962669 | 0.88 | AGER (0.58) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5925528 | 0.87 | HTT (0.56) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10827981 | 0.87 | HTT (0.56) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7367528 | 0.85 | TDP1 (0.59) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20920574 | 0.85 | AGER (0.62) | HTTHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2337975 | 0.84 | HTT (0.67) | HTTHPGDALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977827-A | Methoxychlor-pram intermediate and preparation method and application thereof | 河南优凯制药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119977828-A | Methoxychlor-pup Process for the preparation of amines | 河南优凯制药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119912358-A | Methoxychlor N-ethyl compound and preparation method and application thereof | 河南优凯制药有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119822987-A | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-117843520-A | Methoxychlor-pram intermediate and preparation method and application thereof | 常熟泓德生物科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-113233992-A | Preparation method of 5-chloro-4-acetamido-2-methoxybenzoic acid methyl ester | 江苏巨莱生物医药有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-105523952-A | Preparation method of methyl 4-acetamido-5-chloro-2-methoxybenzoate | JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD | 2016-04-27 | — | — | CN | claimed |
| US-12617780-B2 | Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting | CTXT PTY LTD (AU) | 2026-05-05 | — | — | US | disclosed |
| CN-119822987-B | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2026-03-24 | — | — | CN | disclosed |
| CN-119822987-B | Preparation method of 4-acetamido-5-chloro-2-methoxybenzoic acid methyl ester | 苏州诚和医药化学有限公司 | 2026-03-24 | — | — | CN | disclosed |
| US-12576055-B2 | Disease detection and treatment based on trimethyl-lysine levels | THE CLEVELAND CLINIC FOUNDATION (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4638460-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING | Aculeus Therapeutics Pty Ltd (AU) | 2025-10-29 | — | — | EP | disclosed |
| CN-119977827-A | Methoxychlor-pram intermediate and preparation method and application thereof | 河南优凯制药有限公司 | 2025-05-13 | — | — | CN | disclosed |
| WO-1989010364-A1 | DIBENZOFURANCARBOXAMIDES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0339950-A2 | Dibenzofurancarboxamides, their use as pharmaceutical agents, a composition containing the same, and a process for the preparation thereof | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| US-4863921-A | Dibenzofurancarboxamides and their pharmaceutical compositions and methods | RORER PHARMACEUTICAL CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4835172-A | Novel benzamides, intermediates and process for the preparation and therapeutic use thereof | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1989-05-30 | — | — | US | disclosed |
| US-4163789-A | Anti-psychotic (cycloalkenylalkylpiperidino) benzamides | ANPHAR, S.A. (ES) | 1979-08-07 | — | — | US | disclosed |
| US-4138492-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | ANPHAR, S.A. (ES) | 1979-02-06 | — | — | US | disclosed |
| US-4029673-A | N-(1-benzyl pyrrolidinyl 2-alkyl) substituted benzamides and derivatives thereof | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576055-B2 | Disease detection and treatment based on trimethyl-lysine levels | BHMT, BHMT2, EHMT2 | HTT 1960/4885HPGD 3148/4885ALDH1A1 1296/4885 |
| US-12617780-B2 | Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting | STING1, CGAS, IRF3 | HTT 4402/4885HPGD 2891/4885ALDH1A1 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.