Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464014 | 1.00 | ALOX15 (0.55) | ALOX15TSHRALDH1A1CHRM2CHRM4 | |
| SCHEMBL12215438 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL14826010 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL14815406 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL1171362 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL1302069 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL12215439 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL1171361 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL18076324 | 0.89 | ALOX15 (0.53) | ALOX15ALDH1A1MAPT | |
| SCHEMBL1617388 | 0.85 | ALOX15 (0.57) | ALOX15TSHRALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277012-A1 | DUPLICATE BEVERAGE | WANG JIE (US) | 2024-08-22 | — | — | US | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-20110266361-A1 | PHEROMONE DISPENSER | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |
| US-5585252-A | CATALYTIC ACYLATION OF ALCOHOLS | G. D. SEARLE & CO. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0560408-A1 | Enantio- and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents | G.D. SEARLE & CO. (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5106750-A | Enzymatic resolution of hydroxycyclopentenones using lipase | G. D. SEARLE & CO. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0357009-A2 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | G.D. Searle & Co. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0131254-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRAHYDROFURANES | L. GIVAUDAN & CIE Société Anonyme (CH) | 1988-05-25 | — | — | EP | disclosed |
| US-4560811-A | LEWIS ACID CATALYST, CHIRAL GLYCOL, PEROXY COMPOUNDS, OLEFINS OREPOXZIDES; INTERMEDIATES FOR DRUGS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0131254-A2 | Process for the preparation of substituted tetrahydrofuranes | L. GIVAUDAN & CIE Société Anonyme (CH) | 1985-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALOX15 3088/4885TSHR 3246/4885ALDH1A1 978/4885 |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | ALOX15 2698/4885TSHR 2120/4885ALDH1A1 1490/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALOX15 3088/4885TSHR 3246/4885ALDH1A1 978/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | ALOX15 1520/4885TSHR 2063/4885ALDH1A1 1029/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALOX15 3088/4885TSHR 3246/4885ALDH1A1 978/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALOX15 3088/4885TSHR 3246/4885ALDH1A1 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.