Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717146 | 0.84 | ERN1 (0.52) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL766081 | 0.83 | ERN1 (1.00) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29672629 | 0.83 | ERN1 (1.00) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11575963 | 0.80 | ALDH1A1 (0.56) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1609231 | 0.79 | LMNA (0.46) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1669597 | 0.79 | ALDH1A1 (0.50) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4998777 | 0.79 | MAPT (0.56) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12492120 | 0.79 | ERN1 (0.69) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29607767 | 0.78 | ERN1 (0.60) | ERN1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6981731 | 0.78 | ERN1 (0.60) | ERN1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | claimed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | claimed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | claimed |
| EP-2385947-A1 | TIME TEMPERATURE INDICATOR COMPRISING INDOLENIN BASED SPIROPYRANS | BASF SE (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-20110269242-A1 | TIME TEMPERATURE INDICATOR COMPRISING INDOLENIN BASED SPIROPYRANS | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | disclosed |
| WO-2010079114-A1 | TIME TEMPERATURE INDICATOR COMPRISING INDOLENIN BASED SPIROPYRANS | BASF SE (DE) | 2010-07-15 | — | — | WO | disclosed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | disclosed |
| US-20100022524-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY | 2010-01-28 | — | — | US | disclosed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269242-A1 | TIME TEMPERATURE INDICATOR COMPRISING INDOLENIN BASED SPIROPYRANS | TTN, CCNI, TPH1 | ERN1 2429/4885MEN1 2519/4885KMT2A 1072/4885 |
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | PDLIM5, PSD, PDCD6IP | ERN1 2349/4885MEN1 3762/4885KMT2A 2830/4885 |
| US-20100022524-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | QTRT1, QTRT2, NQO2 | ERN1 1952/4885MEN1 2817/4885KMT2A 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.