Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 12/20 | 0.47 |
| ▸ | CA1 | P00915 | 11/20 | 0.46 |
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELF3 | P78545 | 2/20 | 0.40 |
| ▸ | MED23 | Q9ULK4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657220 | 0.90 | CA9 (0.58) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17210588 | 0.76 | USP2 (0.50) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12657852 | 0.74 | CA9 (0.57) | CA9CA1CA2CA12CA14 | |
| SCHEMBL1103795 | 0.74 | USP2 (0.69) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17067944 | 0.73 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12909301 | 0.73 | USP2 (0.68) | CA9CA1CA2CA12ESR1 | |
| SCHEMBL17903564 | 0.73 | CA9 (0.53) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14211562 | 0.72 | CA9 (0.44) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14642993 | 0.71 | CA1 (0.56) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17893674 | 0.70 | KDM4E (0.49) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256133-A1 | Bioconjugation of macromolecules | Sigma-Aldrich Co. (US) | 2010-12-01 | — | — | EP | disclosed |