Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 9/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903994 | 0.87 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17903544 | 0.77 | USP2 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17210588 | 0.71 | USP2 (0.50) | MEN1KMT2ACA9CA1CA2 | |
| SCHEMBL17067944 | 0.71 | CA9 (0.61) | MEN1KMT2ACA9CA1CA2 | |
| SCHEMBL15496806 | 0.71 | CA9 (0.55) | MEN1KMT2ACA9CA1CA2 | |
| SCHEMBL13019272 | 0.70 | CA9 (0.47) | MEN1KMT2ACA9CA1CA2 | |
| SCHEMBL16808265 | 0.69 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17903564 | 0.68 | CA9 (0.53) | MEN1KMT2ACA9CA1CA2 | |
| SCHEMBL14642993 | 0.67 | CA1 (0.56) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14852664 | 0.67 | CA9 (0.58) | CA9CA1CA2CA12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180244643-A1 | HIGHLY SENSITIVE DETECTION OF BIOMOLECULES USING PROXIMITY INDUCED BIOORTHOGONAL REACTIONS | UNIV CALIFORNIA (US) | 2018-08-30 | — | — | US | disclosed |
| WO-2016109733-A1 | HIGHLY SENSITIVE DETECTION OF BIOMOLECULES USING PROXIMITY INDUCED BIOORTHOGONAL REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244643-A1 | HIGHLY SENSITIVE DETECTION OF BIOMOLECULES USING PROXIMITY INDUCED BIOORTHOGONAL REACTIONS | ICAM1, TLL1, TTL | KDM4E 4379/4885ALDH1A1 1295/4885HPGD 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.