SCHEMBL13019490

SCHEMBL13019490

O=C(c1ccccc1)c1ccc(-c2ccc(-c3ccc(-c4ccncc4)cc3)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.76
MEN1 O00255 2/20 0.76
LMNA P02545 2/20 0.64
MAPT P10636 1/20 0.64
RAB9A P51151 1/20 0.64
ALDH1A1 P00352 2/20 0.58
NOTUM Q6P988 1/20 0.56
POLB P06746 2/20 0.56
STAT3 P40763 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 3/20 0.56
ROCK2 O75116 2/20 0.56
RPS6KA5 O75582 2/20 0.56
MAP4K4 O95819 2/20 0.56
PRKACA P17612 2/20 0.56
RPS6KB1 P23443 2/20 0.56
AKT1 P31749 2/20 0.56
GSK3A P49840 2/20 0.56
GSK3B P49841 2/20 0.56
PRKX P51817 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27623995 0.91 HDAC1 (0.63) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL229650 0.87 KMT2A (1.00) KMT2AMEN1LMNARAB9AALDH1A1
SCHEMBL13019488 0.87 RAB9A (0.82) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL197633 0.87 RAB9A (0.82) KMT2AMEN1LMNAMAPTRAB9A
Benzophenone SCHEMBL28231198 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL29143580 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL28246134 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL13534566 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A
Benzene SCHEMBL28384085 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL41657 0.84 RAB9A (0.78) KMT2AMEN1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905260-B2 Method for manufacturing optical information recording medium FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed
US-9905260-B2 Method for manufacturing optical information recording medium FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed
US-9711176-B2 Multilayer optical information recording disk and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-07-18 US disclosed
US-9711176-B2 Multilayer optical information recording disk and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-07-18 US disclosed
US-9514779-B2 Method for manufacturing multilayer structure sheet, and optical information recording medium FUJIFILM CORPORATION (JP) 2016-12-06 US disclosed
US-9514779-B2 Method for manufacturing multilayer structure sheet, and optical information recording medium FUJIFILM CORPORATION (JP) 2016-12-06 US disclosed
US-20150364153-A1 METHOD FOR MANUFACTURING OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-20150364153-A1 METHOD FOR MANUFACTURING OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-20150318013-A1 MULTILAYER OPTICAL INFORMATION RECORDING DISK AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-20150318013-A1 MULTILAYER OPTICAL INFORMATION RECORDING DISK AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2015-11-05 US disclosed
US-20130128710-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
US-20130128710-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
US-20130100791-A1 OPTICAL INFORMATION RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-25 US disclosed
US-20130100791-A1 OPTICAL INFORMATION RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-25 US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND SIGMAR1, SFN, CRY2 KMT2A 2492/4885MEN1 1622/4885LMNA 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.