Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751788 | 0.80 | PIK3CG (0.38) | KDM4EPIK3CGLRRK2 | |
| SCHEMBL179342 | 0.78 | LRRK2 (0.44) | KDM4ELRRK2 | |
| SCHEMBL13058597 | 0.76 | SQOR (0.40) | — | |
| SCHEMBL16476777 | 0.72 | — | — | |
| SCHEMBL1109104 | 0.71 | KDM4E (0.39) | KDM4EPIK3CGLRRK2 | |
| SCHEMBL21048252 | 0.71 | PIK3CG (0.37) | KDM4EPIK3CGLRRK2 | |
| SCHEMBL12186825 | 0.71 | LRRK2 (0.47) | KDM4ELRRK2 | |
| SCHEMBL6719246 | 0.71 | PIK3CG (0.33) | KDM4EPIK3CGLRRK2 | |
| SCHEMBL18195530 | 0.71 | ALDH1A1 (0.37) | KDM4EDHODH | |
| SCHEMBL21719349 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | KDM4E 3763/4885PIK3CA 3768/4885MTOR 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.