Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.38 |
| ▸ | IGF2R | P11717 | 4/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26943038 | 0.87 | FBP1 (0.53) | FBP1AMDHD2IGF2R | |
| SCHEMBL12354860 | 0.87 | FBP1 (0.53) | FBP1AMDHD2IGF2R | |
| SCHEMBL15624969 | 0.86 | FBP1 (0.52) | FBP1AMDHD2IGF2RFUCA1 | |
| SCHEMBL13020673 | 0.83 | FBP1 (0.34) | FBP1AMDHD2 | |
| SCHEMBL16750151 | 0.81 | FBP1 (0.43) | FBP1AMDHD2IGF2R | |
| SCHEMBL14619325 | 0.75 | FBP1 (0.56) | FBP1AMDHD2IGF2R | |
| SCHEMBL16691820 | 0.73 | FUCA1 (0.37) | FUCA1 | |
| SCHEMBL23960812 | 0.73 | FBP1 (0.75) | FBP1AMDHD2IGF2R | |
| SCHEMBL14985153 | 0.73 | FBP1 (0.75) | FBP1AMDHD2IGF2R | |
| SCHEMBL15765675 | 0.73 | FBP1 (0.75) | FBP1AMDHD2IGF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331397-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | ALIOS BIOPHARMA, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331397-A1 | 2-5A ANALOGS AND THEIR METHODS OF USE | RNASEL, RNASE1, RNASEH1 | FBP1 846/4885AMDHD2 372/4885IGF2R 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.