⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021606 | 0.95 | ALDH1A1 (0.34) | — | |
| SCHEMBL11854214 | 0.66 | MAOA (0.44) | — | |
| SCHEMBL13021597 | 0.63 | — | — | |
| SCHEMBL3208997 | 0.62 | POLB (0.42) | — | |
| SCHEMBL21586529 | 0.62 | MAPT (0.43) | — | |
| SCHEMBL3800030 | 0.59 | DRD4 (0.37) | — | |
| SCHEMBL2081489 | 0.59 | — | — | |
| SCHEMBL24428893 | 0.59 | CES1 (0.39) | — | |
| SCHEMBL22361203 | 0.59 | RAPGEF4 (0.44) | — | |
| SCHEMBL21892964 | 0.59 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096850-A1 | PHOSPHOINOSITIDE 3 KINASE GAMMA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| US-20100286360-A1 | POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286360-A1 | POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |