SCHEMBL24428893

SCHEMBL24428893

Cc1ccc2c(c1C)CCC2

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.39
DRD4 P21917 3/20 0.39
PARP1 P09874 1/20 0.38
POLB P06746 2/20 0.37
BCL2L1 Q07817 1/20 0.37
BAD Q92934 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.36
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
HTR2C P28335 1/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DRD2 P14416 2/20 0.33
MITF O75030 1/20 0.33
MAPT P10636 1/20 0.33
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599446 0.95 CES1 (0.43) CES1DRD4PARP1BCL2L1BAD
SCHEMBL28759083 0.87 KIF11 (0.34) CES1HTR2CSMN1; SMN2
SCHEMBL13091621 0.79 NOS3 (0.39) CES1DRD4PARP1POLBBCL2L1
SCHEMBL22102574 0.79 PNMT (0.43) CES1PARP1BCL2L1BADHTR2C
SCHEMBL14947901 0.79 PARP1 (0.39) CES1DRD4PARP1POLBBCL2L1
SCHEMBL30047413 0.79 BCL2L1 (0.47) CES1PARP1POLBBCL2L1BAD
SCHEMBL23944932 0.78 PARP1 (0.46) CES1PARP1BCL2L1BADRAPGEF4
SCHEMBL17462479 0.78 ADRA2A (0.48) DRD4HTR2CDRD2
SCHEMBL15502922 0.78 HTR2C (0.50) HTR2C
SCHEMBL11325808 0.78 PNMT (0.54) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3605629-B1 ORGANIC SEMICONDUCTOR ELEMENT, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM PRODUCTION METHOD, ORGANIC SEMICONDUCTOR FILM, AND COMPOUND AND POLYMER USED THEREFOR FUJIFILM CORP (JP) 2022-05-18 EP disclosed