SCHEMBL13023969

SCHEMBL13023969

Cc1cc(C)c(N2c3ccncc3Oc3cccnc32)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
CYP2A6 P11509 2/20 0.31
PIM1 P11309 4/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.31
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023972 0.90 KMT2A (0.32) KMT2ACYP2A6LMNATSHRPOLB
SCHEMBL13023981 0.87 LMNA (0.36) LMNAPOLBTP53MAPTSMN1; SMN2
SCHEMBL13024006 0.86 PIM1 (0.32) PIM1MAPT
SCHEMBL13023996 0.86 POLB (0.33) LMNAPOLBMAPT
SCHEMBL13023574 0.85 RAPGEF4 (0.34) LMNAPOLBTP53MAPTSMN1; SMN2
SCHEMBL13023971 0.85 MAPT (0.35) KMT2APIM1NPC1TP53MAPT
SCHEMBL13023978 0.84 MAPT (0.36) PIM1TP53MAPTSMN1; SMN2
SCHEMBL13023997 0.84 RPS6KA5 (0.30) KMT2A
SCHEMBL13024007 0.84 MAPT (0.30) MAPT
SCHEMBL13024009 0.82 PIM1 (0.31) PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 KMT2A 2070/4885CYP2A6 2054/4885PIM1 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.