SCHEMBL13023972

SCHEMBL13023972

Cc1cc(C)c(N2c3cnccc3Oc3cccnc32)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
CYP2A6 P11509 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023969 0.90 KMT2A (0.32) KMT2ACYP2A6POLBMAPTLMNA
SCHEMBL13023996 0.89 POLB (0.33) POLBMAPTLMNA
SCHEMBL13023981 0.87 LMNA (0.36) POLBMAPTLMNATP53SMN1; SMN2
SCHEMBL13023574 0.85 RAPGEF4 (0.34) POLBMAPTLMNATP53SMN1; SMN2
SCHEMBL13023975 0.85 RAPGEF4 (0.34) KMT2AMAPTNPC1TP53RAB9A
SCHEMBL13023993 0.85
SCHEMBL13023980 0.84 MAPT (0.36) MAPTLMNANPC1TP53RAB9A
SCHEMBL13023994 0.84 MAPT (0.31) POLBMAPT
SCHEMBL13023999 0.83 LMNA (0.35) POLBMAPTLMNA
SCHEMBL13023988 0.82 LMNA (0.38) CYP2A6POLBMAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 KMT2A 2070/4885CYP2A6 2054/4885POLB 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.